1999年

1

1

Effect of lead on the synthesis of tissue plasminogen activator by vascular endothelial cells in culture

Yamamoto, C., and Kaji, T

Fujiwara, Y., Mikami, C., Nagai, M., Yamamoto, C., Hirooka, T., Satoh, M. and Kaji, T.

Journal of Health Science, 45, 119-125, 1999

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1997年

5

Cadmium induces the production of high molecular weight heparan sulfate proteoglycan molecules in cultured vascular endothelial cells

Ohkawara, S., Yamamoto, C., Fujiwara, Y., Sakamoto, M., and Kaji, T.

Environmental Toxicology and Pharmacology, 3, 187-194, 1997

4

Tolerance to cadmium cytotoxicity is induced by zinc through non-metallothionein mechanisms as well as metallothionein induction in cultured cells

Mishima, A., Yamamoto, C., Fujiwara, Y., and Kaji, T.

Toxicology, 118, 85-92, 1997

3

Lead-induced alteration of heparan sulfate proteoglycans in cultured vascular endothelial cells

Kaji, T., Ohkawara, S., Nakajima, M., Yamamoto, C., Fujiwara, Y., Miyajima, S., and Koizumi, F.

Toxicology, 118, 1-10, 1997

2

Lead perturbs the regulation of spontaneous release of tissue plasminogen activator and plasminogen activator inhibitor-1 from vascular smooth muscle cells and fibroblasts in culture

Yamamoto, C., Miyamoto, A., Sakamoto, M., and Kaji, T.

Toxicology, 117, 153-161, 1997

1

Basic fibroblast growth factor-induced glycosaminoglycan production in cultured vascular endothelial cells results from enhanced protein synthesis mediated by the lipoxygenase pathway

Kaji, T., Miyamoto, A., Yamamoto, C., Fujiwara, Y., Miyajima, S., and Koizumi, F.

Life Sciences, 60, 873-881, 1997.

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1996年

7

Metallothionein-independent protection by low levels of zinc against cadmium cytotoxicity in cultured cells

Mishima, A., Yamamoto, C., Fujiwara, Y., and Kaji, T.

Research Communications in Pharmacology and Toxicology, 1, 199-210, 1996

6

Sensitive response of cultured vascular smooth-muscle cells to cadmium cytotoxicity: comparison with cultured vascular endothelial cells and kidney epithelial LLC-PK1 cells

Kaji, T., Suzuki, M., Yamamoto, C., Imaki, Y., Miyajima, S., Fujiwara, Y., Sakamoto, M., and Kozuka, H.

Toxicology Letters, 89, 131-137, 1996

5

Cyclic AMP-dependent pathway that mediates suppressive regulation of glycosaminoglycan production in cultured vascular endothelial cells

Kaji, T., Inada, M., Yamamoto, C., Fujiwara, Y. and Koizumi, F.

Thrombosis Research, 82, 389-397, 1996

4

Phorbol 12-myristate 13-acetate stimulates the release of glycosaminoglycans from cultured vascular endothelial cells: Possible involvement of protein kinase C activation

Fujii, N., Kaji, T., Yamamoto, C., Fujiwara, Y., and Koizumi, F.

Thrombosis Research, 82, 379-387, 1996

3

Bismuth induces metallothionein but does not protect against cadmium cytotoxicity in cultured vascular endothelial cells

Kaji, T., Mishima, A., Yamamoto, C., Fujiwara, Y., Sakamoto, M., Kozuka, H., and Koizumi, F.

Bulletin of Environmental Contamination and Toxicology, 56, 630-634, 1996

2

Interaction between cadmium and zinc on the production and the sulfation of glycosaminoglycans in cultured vascular endothelial cells

Ohkawara, S., Kaji, T., Yamamoto, C., Fujiwara, Y., Sakamoto, M., and Kozuka, H.

Journal of Toxicology and Environmental Health, 47, 183-193, 1996

1

Effects of cadmium on the release of tissue plasminogen activator and plasminogen activator inhibitor type 1 from cultured human vascular smooth muscle cells and fibroblasts

Yamamoto, C., Kaji, T., Sakamoto, M., and Kozuka, H.

Toxicology, 106, 179-185, 1996

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1995年

10

Zinc promotes the repair of wounded monolayer of cultured vascular endothelial cells

Kaji, T., Fujiwara, Y., Sakurai, S., Yamamoto, C., Kozuka, H., and Koizumi, F.

Research communications in molecular pathology and pharmacology, 89, 189-198, 1995

9

Vascular smooth muscle cells in culture are highly sensitive to cadmium cytotoxicity without species-related differences: Comparison with Chang liver cells

Kaji, T., Yamamoto, C., Miyajima, S., Suzuki, M., Fujiwara, Y., Sakamoto, M., and Koizumi, F.

Biological and Pharmaceutical Bulletin, 18, 1392-1395, 1995

8

Induction of metallothionein by thrombin in cultured vascular endothelial and smooth muscle cells

Kaji, T., Yamamoto, C., Suzuki, M., Miyajima, S., Fujiwara, Y., Sakamoto, M., and Koizumi, F.

Biological and Pharmaceutical Bulletin, 18, 1272-1274, 1995

7

Stimulation of cultured vascular smooth muscle cell proliferation by thrombospondin is potentiated by zinc

Kaji, T., Fujiwara, Y., Yamamoto, C., Sakamoto, M., and Kozuka, H.

Biological and Pharmaceutical Bulletin, 18, 1264-1266, 1995

6

Regulation by basic fibroblast growth factor of glycosaminoglycan biosynthesis in cultured vascular endothelial cells

Kaji, T., Hiraga, S., Ohkawara, S., Inada, M., Yamamoto, C., Kozuka, H., and Koizumi, F.

Microvascular Research, 49, 268-276, 1995

5

Stimulatory effect of lead on the proliferation of cultured vascular smooth-muscle cells

Fujiwara, Y., Kaji, T., Yamamoto, C., Sakamoto, M., and Kozuka, H.

Toxicology, 98, 105-110, 1995

4

Comparative cytotoxicity of exogenous cadmium-metallothionein and cadmium ion in cultured vascular endothelial cells

Kaji, T., Mishima, A., Machida, M., Yabusaki, K., Suzuki, M., Yamamoto, C., Fujiwara, Y., Sakamoto, M., and Kozuka, H.

Bulletin of Environmental Contamination and Toxicology, 54, 501-506, 1995

3

Severe damage of cultured vascular endothelial cell monolayer after simultaneous exposure to cadmium and lead

Kaji, T., Suzuki, M., Yamamoto, C., Mishima, A., Sakamoto, M., and Kozuka, H.

Archieves of Environmental Contamination and Toxicology, 28, 168-172, 1995

2

Inhibitory effect of lead on the proliferation of cultured vascular endothelial cells

Kaji, T., Fujiwara, Y., Hoshino, M., Yamamoto, C., Sakamoto, M., and Kozuka, H.

Toxicology, 95, 87-92, 1995

1

Zinc-induced tolerance to cadmium cytotoxicity without metallothionein induction in cultured bovine aortic endothelial cells

Mishima, A., Kaji, T., Yamamoto, C., Sakamoto, M., and Kozuka, H.

Toxicology Letters, 75, 85-92, 1995

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1994年

10

Suppression of plasminogen activator inhibitor type 1 release from cultured human umbilical vein endothelial cells by basic fibroblast growth factor

Kaji, T., Yamamoto, C., Sakamoto, M., Kozuka, H., and Koizumi, F.

Life Sciences, 54, 1563-1569, 1994

9

Calcium regulation of tissue plasminogen activator and plasminogen activator inhibitor-1 release from cultured human vascular endothelial cells

Yamamoto, C., Kaji, T., Sakamoto, M., Kozuka, H., and Koizumi, F.

Thrombosis Research, 74, 163-168, 1994

8

Plasmin-induced reduction of heparan sulfate in cultured vascular endothelial cell layer

Kaji, T., Hiraga, S., Fujii, N., Yamamoto, C., Sakamoto, M., Kozuka, H., and Koizumi, F.

Thrombosis Research, 74, 85-93, 1994

7

Basic fibroblast growth factor suppresses tissue plasminogen activator release from cultured human umbilical vein endothelial cells but enhances that from cultured human aortic endothelial cells

Yamamoto, C., Kaji, T., Furuya, M., Sakamoto, M., and Kozuka, H.

Thrombosis Research, 73, 255-263, 1994

6

Induction of metallothionein synthesis by bismuth in cultured vascular endothelial cells

Kaji, T., Suzuki, M., Yamamoto, C., Imaki, Y., Mishima, A., Fujiwara, Y., Sakamoto, M., and Kozuka, H.

Research Communications in Molecular Pathology and Pharmacology, 86, 25-35, 1994

5

Stimulation by zinc of cultured vascular endothelial cell proliferation: Possible involvement of endogenous basic fibroblast growth factor

Kaji, T., Fujiwara, Y., Yamamoto, C., Sakamoto, M., and Kozuka, H.

Life Sciences, 55, 1781-1787, 1994

4

Cadmium-induced alteration of glycosaminoglycans with an enhancement of heparin-like activity in cultured vascular endothelial cells

Kaji, T., Ohkawara, S., Yamamoto, C., Sakamoto, M., and Kozuka, H.

Toxicology, 94, 161-171, 1994

3

Alteration of glycosaminoglycans induced by cadmium in cultured vascular smooth muscle cells

Kaji, T., Ohkawara, S., Inada, M., Yamamoto, C., Sakamoto, M., and Kozuka, H.

Archives of Toxicology, 68, 560-565, 1994

2

Cadmium stimulation of glycosaminoglycan synthesis by cultured vascular endothelial cells: Comparison of various cell types

Kaji, T., Ohkawara, S., Inada, M., Yamamoto, C., Sakamoto, M., and Kozuka, H.

Biological and Pharmaceutical Bulletin, 17, 454-457, 1994

1

Transforming growth factor beta-induced tolerance to cadmium cytotoxicity in cultured vascular endothelial cells

Kaji, T., Ohkawara, S., Yamamoto, C., Sakamoto, M., and Kozuka, H.

Toxicology, 88, 69-79, 1994

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1993年

6

Characterization of tumor necrosis factor alpha-induced alteration of glycosaminoglycans in cultured cells: Comparison among vascular smooth-muscle cells, vascular endothelial cells. Chang liver cells and LLC-PK1 cells

Kaji, T., Hiraga, S., Yamamoto, C., Okoshi, T., Sakamoto, M., Kozuka, H., and Koizumi, F.

Biological and Pharmaceutical Bulletin, 16, 834-839, 1993

5

Modulation by endothelin-1 of tissue plasminogen activator and plasminogen activator inhibitor-1 release from cultured human vascular endothelial cells: Interaction of endothelin-1 with cytokines

Yamamoto, C., Kaji, T., Sakamoto, M., and Kozuka, H.

Biological and Pharmaceutical Bulletin, 16, 714-715, 1993.

4

Tumor necrosis factor alpha-induced alteration of glycosaminoglycans in cultured vascular smooth-muscle cells

Kaji, T., Hiraga, S., Yamamoto, C., Sakamoto, M., Nakashima, Y., Sueishi, K., and Koizumi, F.

Biochimica et Biophysica Acta, 1176, 20-26, 1993

3

Metallothionein induction by cadmium, cytokines, thrombin and endothelin-1 in cultured vascular endothelial cells

Kaji, T., Yamamoto, C., Tsubaki, S., Ohkawara, S., Sakamoto, M., Sato, M., and Kozuka, H.

Life Sciences., 53, 1185-1191, 1993

2

Cadmium stimulation of plasminogen activator inhibitor-1 release from human vascular endothelial cells in culture

Yamamoto, C., Kaji, T., Sakamoto, M., and Kozuka, H.

Toxicology, 83, 215-223, 1993

1

Zinc protection against cadmium-induced destruction of the monolayer of cultured vascular endothelial cells

Kaji, T., Mishima, A., Yamamoto, C., Sakamoto, M., and Kozuka, H.

Toxicology Letters, 66, 247-255, 1993

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1992年

9

Plasmin stimulates the release of dermatan sulfate from vascular smooth muscle cells in culture

Kaji, T., Hiraga, S., Mishima, A., Yamamoto, C., Sakamoto, M., and Koizumi, F.

Thrombosis Research, 67, 791-799, 1992

8

Effect of endothelin on the release of tissue plasminogen activator and plasminogen activator inhibitor-1 from cultured human endothelial cells and interaction with thrombin

Yamamoto, C., Kaji, T., Sakamoto, M., and Koizumi, F.

Thrombosis Research, 67, 619-624, 1992

7

Endothelin modulation of tissue plasminogen activator release from human vascular endothelial cells in culture

Kaji, T., Yamamoto, C., Sakamoto, M., and Koizumi, F.

Blood Coagulation & Fibrinolysis, 3, 5-10, 1992

6

Possible mechanism for zinc protection against cadmium cytotoxicity in cultured vascular endothelial cells

Kaji, T., Mishima, A., Koyanagi, E., Yamamoto, C., Sakamoto, M., and Kozuka, H.

Toxicology, 76, 257-270, 1992

5

Inhibitory effect of lead on the release of tissue plasminogen activator from human vascular endothelial cells in culture

Kaji, T., Yamamoto, C., Sakamoto, M., and Kozuka, H.

Toxicology, 73, 219-227, 1992

4

Protective effect of copper against cadmium cytotoxicity on cultured vascular endothelial cells

Kaji, T., Fujiwara, Y., Koyanagi, E., Yamamoto, C., Mishima, A., Sakamoto, M., and Kozuka, H.

Toxicology Letters, 63, 13-20, 1992

3

Effect of cadmium on the monolayer maintenance of vascular endothelial cells in culture

Kaji, T., Mishima, A., Yamamoto, C., Sakamoto, M., and Koizumi, F.

Toxicology, 71, 267-276, 1992

Rhodamine B inhibits collagen synthesis by human lip fibroblasts in culture

Kaji, T., Kawashima, T., Yamamoto, C., and Sakamoto, M.

Toxicology Letters, 61, 81-87, 1992

1

Reversibility of the inhibitory effect of rhodamine B on the proliferation of cultured human lip fibroblasts

Kaji, T., Kawashima, T., Yamamoto, C., Sakamoto, M., Kurashige, Y., and Koizumi, F.

Toxicology Letters, 60, 69-74, 1992

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